吴紫云员工，BETWAY必威2002级生物技术专业本科、2006级作物遗传育种专业硕士，2014年毕业于新加坡国立大学，获食品科学与工程博士学位，2014年至2019年于哈佛大学医公司从事博士后研究。2019年至今，上海交通大学长聘教轨副教授。长期专注于食品营养与生物衰老研究，成果显著。在Cell Metabolism, Nature Communications, EMBO Reports, BMC Biology, Journal of Agricultural and Food Chemistry等国际著名期刊共发表论文23篇，受到本领域知名专家学者的高度评价，多次应邀参加国际顶级学术会议。曾获国际食品科技联盟(IUFoST)青年科学家奖“Young Scientist Award”、上海浦江人才计划、上海市海外高层次人才、国家级青年人才等荣誉。 主要研究领域 《食品营养与生物衰老》课题组主要围绕食品营养影响衰老发生与发展的基础科学问题，用酵母、线虫和小鼠等模式生物，结合分子遗传学、生物化学、代谢组和转录组学等技术手段，重点分析饮食影响先天免疫的共性机制，探究食品营养影响长寿的秘诀，解析先天免疫调控衰老的保守机制，以期揭示营养调控衰老的分子机制，为明确回答“吃什么样的食物可能有利于改善慢性炎症和延长寿命？”这一朴实问题提供科学基础，为长寿膳食配方的开发提供理论基础。
近期代表论文：
1.Campos JC#, Wu Z#, Rudich PD, et al. Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling. EMBO reports, 2021, e52964.
2.Wu Z, Isik M, Moroz N, et al. Dietary restriction extends lifespan through metabolic regulation of innate immunity. Cell Metabolism, 2019, 29(5), 1192-1205.Research Highlight by Nature Reviews Endocrinology, 2019, 15(6), 317.Spotlight by Molecular Cell, 2019, 74(5), 864-865.F1000 recommendations: Pankaj Kapahi, “Very Good”F1000 recommendations: Dongsheng Cai, “Exceptional”F1000 recommendations: Thomas Flatt, “Very Good”F1000 recommendations: Siegfried Hekimi, “Exceptional”
3.Wu Z#, Senchuk MM#, Dues DJ, et al. Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways. BMC Biology, 2018, 16, 147.
4.Wu Z, Song L, Liu S and Huang D. Tanshinones extend chronological lifespan in budding yeast Saccharomyces cerevisiae. Applied microbiology and biotechnology, 2014, 98(20), 8617-8628.
5.Wu Z, Liu S, and Huang D. Independent and additive effects of glutamic acid and methionine on yeast longevity. Plos One, 2013, 8(11): e79319.
6.Wu Z, Song L, Feng S, et al. Germination dramatically increases isoflavonoid content and diversity in chickpea (Cicer arietinum L.) seeds. Journal of Agricultural and Food Chemistry. 2012, 60, 8606−8615.
7.Wu Z, Song L, Liu S and Huang D. A high throughput screening assay for determination of chronological lifespan of yeast. Experimental Gerontology. 2011, 46, 915-922.
8.Wu Z, Song L and Huang D. Food grade fungal stress on germinating peanut seeds induced phytoalexins and enhanced polyphenolic antioxidants. Journal of Agricultural and Food Chemistry. 2011, 59, 5993−6003.
个人简介：https://www.agri.sjtu.edu.cn/faculty/41587
